Practice Name

Porcaro Cosmetic Surgery

1943 SE Port St. Lucie Boulevard
Port St. Lucie, FL 34952
Phone: (772) 337-1717
Fax: (772) 337-1737

For Women

 

What Women need to know about Pellet Hormone Therapy,

Dr. John Porcaro, Port St Lucie, FL

Hormone Replacement Therapy, Dr. John Porcaro, Port St Lucie- Why Pellets?

  • Estrogen delivered by subcutaneous pellets maintains the normal ratio of estradiol to estrone (2:1), important for optimal health and disease prevention.
  • Pellets do NOT increase the risk of blood clots or breast cancer like conventional synthetic HRT.
  • Pellets are far superior to oral hormone replacement therapy, especially with respect to bone density, insomnia, sex drive, libido, and sexual performance.
  • Pellets result in an extremely high level of symptomatic relief.
  • Pellets are the most convenient method of hormone delivery.

Problems with Oral (conjugated; synthetic) Estrogens:

Premarin, Prephase, Prempro (pills)

  • Horse (urine)=Equilin
  • Human female=Estradiol
  • Changes normal estrogen ratio in the body
  • Increases estrone;
  • a very strong breast stimulator (breast tenderness)
  • water retention
  • weight gain- waist & hips
  • increase in breast cancer.
  • Produce “roller coaster” effect
  • Reverses the normal physiologic ratio of estradiol/estrone from 2:1 to 1:2
  • Breast stimulators
  • Fluid retention and weight gain
  • “First pass” metabolism through the liver necessitates a much higher dose
  • Take “something” every day; poor compliance
  • Increase the chance of breast cancer after 10 yrs.

Potential and Unnecessary Effects of Oral Estrogen Therapy: Breast Tenderness, Increased risk of endometrial cancer and breast cancer, Vaginal bleeding, Headaches, Nausea and Vomiting, Fluid retention, Blood clots, Leg cramps, Gallstones

Osteoporosis- Bone Density- Hormone Replacement Therapy, Dr. John Porcaro, Port St Lucie:

  • Pellets demonstrated 8x increase in bone density over oral estrogen and 2.5x increase over patches
  • 1-2 % per year for oral estrogen
  • 3.5% per year for patches
  • 8.3% per year for Pellet therapy

Studd, J WW, et al (1990)
Am Journal OB/GYN 163, 1474-1479

 

Problems with Patches: Adhesive problems –don’t stick; allergy, change them once or twice weekly, some weight gain, but less fluid retention, estradiol levels better than pills, but not as good as pellets.

 Breast Cancer Incidence with Pellets since 1992-2002

 

Time on
Pellet HRT
Number of
Patients Total
Cases of
Breast Cancer
0-2 years
352
1
3-5 years
471
0
5-25 years
153
0
 
976
1

 

Positive Effects of Bio-Identical Testosterone- Bio-Equivalent Hormone Replacement Therapy Port St LucieBio-Equivalent Hormone Replacement Therapy Port St Lucie

  • Enhanced libido
  • Cardiovascular protection
  • Lower cholesterol
  • Increased energy and vitality
  • Feeling of overall well-being
  • Reducing body fat
  • Stronger bones and muscles
  • Depression relief
  • Cognitive clarity

The Goal for Hormone Replacement Therapy, Dr. John Porcaro: To produce a normal, premenopausal FSH level thereby alleviating symptoms and reinstating normal female physiology.

Estradiol Pellets: The only form of HRT that produces continuous suppression of FSH over a four to six month period.

 Testosterone Pellets: The only form of testosterone therapy that recreates the physiologic levels of testosterone in both men and women

 Hormone Replacement Therapy, Dr. John Porcaro, Port St Lucie

 

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